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我公司需要麻醉、精神类的药品用户核查制度和流向跟踪核查制度的范本吗？如有请投标   [更多]

方法的要求：可采用HPLC、GC等常用方法。不能采用毛细管电泳方法。 药物名称及结构式： ［中文通用名］：甘磷酸胆碱 ［英文通用名］：Choline Alfoscerate ［商品名］：Gliatilin、Delecit、Brezal ［化学结构式］： 分子式：C8H20NO6P 分子量：257.23 ［CAS  RN］：28319-77-9 ［英文化学名］：Ethanaminium, 2-[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, hydroxide, inner salt, (R)- [CAS]   [更多]

这个任务要求提供一种测试方法，能够简单的检测出血友病A 中凝血因子Ⅷ和血友病B 中凝血因子IX在血液中的水平。因为现在市面上所使用的测试方法都不太方便，都不适用于诊所，而且患者也不能在家里进行自我检测。这个任务要求提供一个半定量的测试方式，需要提供可靠的血液中凝血因子水平的资料，然后根据情况分为正常，轻微，严重三种疾病状态。 　　“征稿件请直接上传网址：https://www.innocentive.com” 　　TAGS: Engineering/Design, Chemistry, Global Health, Nature, Life Sciences, Food/Agriculture, Theoretical-IP Transfer 　　AWARD: $25,000 USD | DEADLINE: 2/21/13 | ACTIVE SOLVERS: 27 | POSTED: 12/21/12 　　The Seeker requires a test that could easily be used to monitor the level of blood coagulation factors FVIII or FIX present in hemophilia A and B patients, respectively. Today, many tests are commercially available, but none are suited for convenient testing either by care providers in the clinic or by hemophilia patients at home. A semi-quantitative test is required that would provide reliable information on the blood levels of FVIII or FIX relative to a state considered as ‘Normal’, ‘Mild’ or ‘Severe’ state of disease. 　　This Challenge requires only a written proposal. 　　Detailed Description & Requirements 　　Background 　　Hemophilia A and B are inherited coagulation diseases that severely impact the quality of life of persons afflicted. Hemophilia A is caused by lack of coagulation factor VIII (FVIII), while in hemophilia B patients lack coagulation factor IX (FIX). Although the diseases are to a large extent manageable using clotting factor supplement therapies, FVIII and FIX treatment needs to be monitored in order to ensure that it meets the requirements of the individual patients’ plasma level of the coagulations factor to be supplemented. Current tests require tedious laboratory analysis, not allowing patients to achieve the frequency of testing that would facilitate good management of their disease. 　　The Problem 　　Hemophilia patients are expected to benefit from daily monitoring of their disease status (i.e. measurements of FVIII or FIX levels) to check the efficacy of their therapy and the current status of their disease.   [更多]

维生素EC咀嚼片(北京四环科宝)检验记录， 北京市药检所检验，05-06年检验，药厂检验记录也行， 北京四环科宝制药有限公司 受理号：CXHS0501762京 注意一下，要的是检验记录而不是检验报告，主要是想获得药品的片重，因为目前市场上这个品种没有销售 联系qq号：393987918   [更多]

需要意大利药典标准的匹多莫德口服溶液的标准，不是欧洲药典的，如果有请报价   [更多]

PXE国际关于弹性假黄瘤(PXE)的研究团队，对其的病因提出了现有的两种假设：积极的循环代谢产物或者组织特异性功能障碍。任务要求提供数据来求证这两种假设或其中之一。根据各地的发病机制进行实验，进一步了解PXE的病因。 这项任务保证至少会奖励一名挑战者，并且，除了任务奖金之外，PXE国际还将对中标者给予PXE的研究经费资助。 征稿件请直接上传网址：https://www.innocentive.com PXE – Evaluating Hypotheses and Suggesting Experiments for a Rare Disease TAGS: Computer Science/Information Technology, Chemistry, Global Health, Nature, Public Good, Life Sciences, Ideation AWARD: $7,000 USD | DEADLINE: 11/30/12 | ACTIVE SOLVERS: 38 | POSTED: 10/31/12 The Seeker, PXE International, the primary group responsible for funding PXE research, presents two existing hypotheses (an active circulating metabolite(s) or a tissue-specific dysfunction) for the rare disease Pseudoxanthoma Elasticum (PXE). The Seeker requests that Solvers present evidence favoring one of the two hypotheses, then provide additional experiments to conduct to further knowledge around the disease mechanism. This is an Ideation Challenge with a guaranteed award for at least one submitted solution. In addition to the Challenge award, PXE International will also assist finalists in efforts to obtain funding for PXE-related research. Detailed Description & Requirements INTRODUCTION TO PXE Pseudoxanthoma Elasticum (PXE) is a recessive genetic disorder with signs and symptoms that mimic many aspects of the normal aging process, but at a much younger age (when people are roughly between 10 and 20 years old). Specifically, the disease is characterized by fragmentation and mineralization of elastic fibers in certain tissues. Some of the more common symptoms, in general order that they occur, are: Wet-type macular degeneration Skin wrinkling Calcification of blood vessels Cardiovascular disease PXE is a rare disease with an estimated patient population of 12,000 people. Given the small number of people with the disease, it has not been the subject of research by for-profit pharmaceutical and biotech companies.   [更多]

这项任务要要求设计一个自动化的，高通量的仪器 ， 可以定量地和可重复地测定的油水乳化液的分离。 这个任务需要提交一份书面建议书。 An Instrument for Quantitative, Reproducible Characterization of Water/Oil Emulsions AWARD: $30,000 USD | DEADLINE: 10/15/12 | ACTIVE SOLVERS: 508 | POSTED: 8/15/12 Source: InnoCentive Challenge ID: 9933086 Type: Theoretical-IP Transfer Detailed Description & Requirements The presence of emulsions in oil operations is common and generally undesirable. Crude oil emulsions typically form due to the presence of naturally occurring emulsifying agents (asphaltenes, resins, etc.) in crude oil. The high cost associated with transportation and corrosion of equipment is one of the problems caused by the presence of water in the crude oil. Therefore, oil dehydration is required, which is often achieved through chemical treatment using demulsifiers. While the Seeker has identified ~200 liquid “demulsifier” agents, compounds that in amounts of ~100-500 ppm can aid in the resolution of the water and oil phases, they lack a quantitative and reproducible assay for determining demulsifier effectiveness at resolving the emulsion. Currently, the Seeker performs a “bottle test” in which they add ~15-100 mL of the emulsion into a bottle, add the different demulsifiers, shake, and then visually observe which bottles show the best phase separation. This assay clearly relies on visual detection by a trained observer and is not nearly as quantitative or reproducible as the Seeker desires. Results from a bottle test with the same emulsion and three different demulsifiers are shown below. The bottle on the left has clearly not been resolved into two distinct phases. While the middle bottle shows significant improvement, careful inspection of the phase boundary shows a slight amount of oil contaminating the water layer and a slightly undefined interface. Finally, the bottle on the right shows an optimally resolved two-phase system with a very clear oil/water phase boundary. Important Note:   [更多]

任务材料需要提供与化合物相匹配的核心结构和每种化合物合成的详细的参考依据。合格者会得到一定的奖励。将给予每种化合物知识产权转让费9000元，非独家许可使用化合物，以达到研究目的，比如：研究化合物分子的性质和分子衍生物。 Seeking Bicyclic Aminoketones AWARD: varies | DEADLINE: 10/22/12 | ACTIVE SOLVERS: 24 | POSTED: 9/21/12 Source: InnoCentive Challenge ID: 9932910 Type: RTP Detailed Description & Requirements Intellectual Property: In return for the Initial Transfer Fee of $1,500 per compound, you are expected to grant the Seeker only a non-exclusive license to use your compound for internal, research purposes (for example, researching the molecule’s properties or preparing derivatives of the molecule). Material supply of non-commercial compounds matching the shown core structures is desired. For Solvers’ information, procedures for preparing compounds of this type may be found in the following references: Synthesis, 1, 1979, 50. Synthesis, 3, 2010, 493. Tetrahedron, 68 (4), 2012, 1286. J. Organic Chem, 73 (6), 2008, 2114. J. Med. Chem, 37 (18), 1994, 2831. More specifically, the Seeker is looking for compounds that meet the following Requirements: Structure: FeatureRange StructureA bicyclic aminoketone as shown in the structures above. Elements in R and A groupsR = H, Me, or protecting group (preferably Boc) A = A 1-3 membered linker where one atom may be N, O, or S Substituents– In addition to H, the core rings and/or the A linker may be substituted with Me or F. Unsaturation– The core rings and/or the A linker may include an olefin, including an exo olefin, but may not contain any additional carbonyl groups. Additional Rings– The Seeker would prefer compounds that have only the bicyclic structure shown above, however, they may consider compounds with an additional ring fused to the core bicycle. Stereochemistry– The Seeker will only consider compounds which are single diastereomers. In cases where the compound may exist as two enantiomers, the Seeker will consider   [更多]

Disulfiram 我想要一份USP版本的分析单   [更多]

复方丹参片补充检验方法，要求是扫描件 注意是补充检验方法而不是常规标准   [更多]