Coccidiosis is a common disease that affects the intestinal health of poultry worldwide. Susceptible animals exposed to Eimeria strains through fecal-oral transfer develop intestinal lesions that result in low weight gain, poor feed conversion, and mortality. Treatment with anticoccidial drugs has led to resistant strains of Eimeria and vaccination is now the preferred method for prevention. Vaccines elicit a pathogen-specific immune response that protects the animals against further parasitic challenge. Proliferation of these vaccines in live chickens poses a significant cost and a concerning animal welfare issue.
球虫病是一种影响全球家禽肠道健康的常见疾病。通过粪 - 口转移暴露于艾美球虫菌株的易感动物会发生肠道病变，导致体重增加低，饲料转化率低和死亡率低。用抗球虫药物治疗已导致艾美球虫的抗性菌株，并且疫苗接种现在是预防的优选方法。疫苗引发病原体特异性免疫反应，保护动物免受进一步的寄生虫攻击。这些疫苗在活鸡中的增殖造成了巨大的成本和涉及动物福利的问题。
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