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①文献和网站来源必须权威、专业，尽量找外文或官网的文献或报道，不能是百度百科等； ②简要概述的语句具有逻辑性和连贯性。 ③由于药物本身存在信息不全或难找到信息源，以及药物概述质量不定（如翻译质量不定等）的情况，赏金酌情给出，请谅解。 ④单价8元/条，质量偏低需折价计算。 32个合格5个内容偏少，32*8+5*4=276 *此任务金额为不含税金额，按照国家税务相关法律法规，提现时个税由药智汇代扣代缴   [更多]

1、Ophthalmic viscosurgical devices Article· Literature Review in Current Opinion in Ophthalmology 19(1):50-4 · February 2008 with 82 Reads DOI: 10.1097/ICU.0b013e3282f14db0 · Source: PubMed 2、Lancet Psychiatry. 2019 Mar;6(3):211-224. doi: 10.1016/S2215-0366(18)30511-X. Epub 2019 Feb 18. Prevalence of mental disorders in China: a cross-sectional epidemiological study. Huang Y1, Wang Y2, Wang H3, Liu Z4, Yu X4, Yan J5, Yu Y6, Kou C6, Xu X7, Lu J7… PMID:30792114 3、Prevalence of myopia in local and international schools in Hong Kong. 4、Effects of different concentrations of atropine on controlling myopia in myopic children. 5、Effects of muscarinic cholinergic receptor antagonists on postnatal eye growth of rhesus monkeys 6、Effects of different concentrations of atropine on controlling myopia in myopic children. 7、Use of mechlorethamine gel in patients diagnosed with mycosis fungoides cutaneous T-cell lymphoma (MF-CTCL): “Real-world” experience from the Prospective Observational Study (PROVe) 8、Safety and effectiveness of tolvaptan administration after total arch replacement Yasunori Iida, MD, PhD, Akihiro Yoshitake, MD, PhD, Hideyuki Shimizu, MD, PhD 9、The role of tolvaptan administration after cardiac surgery: ameta-analysisIoannis Bellos MD , Dimitrios C. Iliopoulos MD, PhD ,Despina N. Perrea MD, PhD 10、Comparative bioavailability and in vitro in vivo correlation of two sustained release brands of theophylline: tablets and pellets.Tulain U, Ur-Rahman N.Pak J Pharm Sci. 2008 Apr;21(2):131-8. 11、Relative bioavailability and bioequivalence study of theophylline sustained release formulations. Vergin H, Mahr G, Winterhalter B, Wigand R.Arzneimittelforschung. 2003;53(9):635-9. 12、Use of mechlorethamine gel in patients diagnosed with mycosis fungoides cutaneous T-cell lymphoma (MF-CTCL): “Real-world” experience from the Prospective Observational Study (PROVe) 13、journal of medicinal chemistry 2004,47,530 14、Gupta AK, Ryder JE, Lynch LE et al. The use   [更多]

文献： 1、Journal of Organic Chemistry1961vol. 26p. 2507 - 2510 2、J Contemp Dent Pract. 2016 Dec 1;17(12):1009-1012.Rebamipide to Manage Stomatopyrosis in Oral Submucous Fibrosis.Baptist J1, Shakya S2, Ongole R1. 3、heart failure with preserved ejection fraction：types 1 and 2 ？10.1016/j.jchf.2018.12.017 4、Current status of research on infantile cholestatic liver disease in China: a visualization analysis Author(s): LIAO Qiong, WAN Chao-Min, ZHU Yu, YANG Xiao-Yan, SHU Min, Department of Pediatrics, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University 5、Diagnosis and differential diagnosis of infantile cholestasis disease Author(s): Dong Chen, Huang ZhihuaDong Chen: Department of Pediatrics, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China 6、In vitro dissolution and in vivo bioequivalence evaluation of two brands of isosorbide 5-mononitrate sustained release tablets.Kim YH1, Choi KS, Kam SH, Lee KH, Park JS 7、Evaluation of the bioequivalence and pharmacokinetics of two tablet formulations of isosorbide-5-mononitrate after single oral administration in healthy volunteers. Niopas I1, Daftsios AC, Nikolaidis N. 8、PK/PD analysis of Tebipenem Pivoxil (ME1211),a Novel Oral Carbapenem Antibiotic,in otolaryngological infections,a phase II clinical trial；（新型口服碳青霉烯类抗生素替比培南匹伏酯（ME1211）在耳鼻咽喉感染中的pk/pd分析，一项Ⅱ期临床试验） 9、PK/PD analysis of Tebipenem Pivoxil (ME1211),a Novel Oral Carbapenem Antibiotic,in otolaryngological infections,a phase II clinical trial；（新型口服碳青霉烯类抗生素替比培南匹伏酯（ME1211）在耳鼻咽喉感染中的pk/pd分析，一项Ⅱ期临床试验） 10、Trends in the Management of Acute Heart Failure Requiring Intensive Care Shirakabe A Kobayashi N, kazakh Matsushita M, Shibata Y -, Godah, Shigihara s", AsanKiuchit 11、Patient Selection for Tolvaptan Therapy Among Those With Chronic Kidney Disease and Heart Failure 12、Baumann; Butler;   [更多]

DrugsoftheFuture（DOF）2022年1-3期 文献必须完整、准确（备注：此任务已线下联系好）   [更多]

DrugsoftheFuture（DOF）2020年8-10期 文献必须完整、准确   [更多]

1.Nihon Yakurigaku Zasshi. 2013 Jul;142(1):39-46. doi: 10.1254/fpj.142.39. Pharmacological and clinical properties of AIMIX combination tablets LD&HD, fixed-dose combination of irbesartan and amlodipine besilate. 2.Am J Cardiovasc Drugs. 2013 Apr;13(2):141-50. doi: 10.1007/s40256-013-0014-7. Irbesartan/amlodipine: a review of its use in adult patients with essential hypertension not adequately controlled with monotherapy. 3.Clin Ther. 2012 Aug;34(8):1705-19. doi: 10.1016/j.clinthera.2012.06.026. Epub 2012 Jul 30. I-COMBINE study: assessment of efficacy and safety profile of irbesartan/amlodipine fixed-dose combination therapy compared with amlodipine monotherapy in hypertensive patients uncontrolled with amlodipine 5 mg monotherapy: a multicenter, phase III, prospective, randomized, open-label with blinded-end point evaluation study. 4.Clin Ther. 2012 Aug;34(8):1720-34.e3. doi: 10.1016/j.clinthera.2012.07.001. Epub 2012 Jul 30. I-ADD study: assessment of efficacy and safety profile of irbesartan/amlodipine fixed-dose combination therapy compared with irbesartan monotherapy in hypertensive patients uncontrolled with irbesartan 150 mg monotherapy: a multicenter, phase III, prospective, randomized, open-label with blinded-end point evaluation study. 5.Am J Cardiovasc Drugs. 2013 Apr;13(2):141-50. doi: 10.1007/s40256-013-0014-7. Irbesartan/amlodipine: a review of its use in adult patients with essential hypertension not adequately controlled with monotherapy. 6J Cardiol. 2019 Mar 20. pii: S0914-5087(19)30053-X. doi: 10.1016/j.jjcc.2019.03.001. [Epub ahead of print] Arginine vasopressin antagonism in heart failure: Current status and possible new directions. Goldsmith SR1. 7.Metabolism of Peptide Drugs and Strategies to Improve their Metabolic Stability 8.Expert Rev Neurother. 2017 Jan;17(1):59-75. Epub 2016 Oct 20. Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer's disease pathology. Tramutola A1, Arena A1,   [更多]

具体要求： 1、查找药品信息，补充完整药品对应的所有靶点信息和查找的数据来源网址。药物与机体生物大分子的结合部位即药物靶点。药品作用的靶点信息涉及受体、酶、离子通道、转运体、基因、免疫系统等类型。 2、文献或者网站来源必须权威、专业，需是直接能看到靶点信息的网址或者文章，不能是百度百科； 3、靶点的信息需完整，靶点的写法需是全称加简称； 4、一共83条，单价10元/条，一人完成，共计830元，若在来源中核查不到该药品对应的靶点信息，或者查找不到，该条的悬赏金则扣除，望谅解； 5、完成日期2021年6月4日。 有意者联系本人，联系方式：（微信:qqsslalala;QQ:158224259） 后期会有相同的悬赏任务发布，期待一人长期合作。 *此任务金额为不含税金额，按照国家税务相关法律法规，提现时个税由药智汇代扣代缴。   [更多]

ID：嘻嘻嘻嘿嘿嘿，领取赏金；处理统计之后药智网未收载的说明书数量为23条，已收载的说明书条数为47条，总的赏金=23*5+47*3=256   [更多]

①文献和网站来源必须权威、专业，尽量找外文或官网的文献或报道，不能是百度百科等； ②简要概述的语句具有逻辑性和连贯性。 ③由于药物本身存在信息不全或难找到信息源，以及药物概述质量不定（如翻译质量不定等）的情况，赏金酌情给出，请谅解。 ④单价8元/条，质量偏低需折价计算。 26个合格，11个内容偏少，26*8+11*4=252 *此任务金额为不含税金额，按照国家税务相关法律法规，提现时个税由药智汇代扣代缴   [更多]

①文献和网站来源必须权威、专业，尽量找外文或官网的文献或报道，不能是百度百科等；②简要概述的语句具有逻辑性和连贯性。 ③由于药物本身存在信息不全或难找到信息源，以及药物概述质量不定（如翻译质量不定等）的情况，赏金酌情给出，请谅解。 ④单价8元/条，质量偏低需折价计算。 30个合格，3个内容偏少，30*8+3*4=252*此任务金额为不含税金额，按照国家税务相关法律法规，提现时个税由药智汇代扣代缴   [更多]